Instruction
The main component of Duphaston is dydrogesterone, which is similar to natural progesterone. Doctors recommend taking it to prepare the endometrium of the uterus for a future pregnancy. After its onset, the drug is continued to drink to preserve the embryo.
The drug is prescribed during pregnancy planning. Before taking the drug, it is necessary to pass tests showing the level of progesterone in the body. After it has been proven that the presence of a hormone in the body is less than normal, doctors prescribe Duphaston. To obtain reliable and reliable results about the level of progesterone, the analysis should be taken in the middle of the second phase of the menstrual cycle. A woman needs to track ovulation for three cycles and donate blood in at least two laboratories. You can not start taking the drug during pregnancy and at the planning stage without a proper preliminary examination. "Dufaston" is a hormonal agent and its excess and uncontrolled ingestion into the body greatly harms a woman.
Doctors "Duphaston" are prescribed during pregnancy planning from 11 to 25 days for three to six cycles. This is for those patients whose menstrual cycle is 28 days. In the event of pregnancy after taking Duphaston, you should not interrupt the drug and continue to drink it. A sharp decrease in progesterone leads to a miscarriage. The usual drug during the interesting position is 20 mg twice a day. Cancellation of the hormonal drug should be gradual and occur at about 20 weeks.
Only the attending gynecologist gives an individual treatment regimen. You can not drink "Duphaston", prescribed by a doctor only upon inquiries. Before taking and to clarify miscarriage and infertility, it is imperative to pass a hormone test. In case of a threatened miscarriage, 40 mg of Duphaston may be recommended at a time. Dose adjustment depends on the general condition of the vaginal epithelium.
The drug causes such side effects as headache, nausea, vaginal bleeding, dizziness and allergies. Those who have previously taken birth control pills should be more careful about taking Duphaston. Since the combination of progestin with estrogen increases the risk of thrombosis. The hormonal agent is contraindicated in women with liver and heart diseases. Also, Duphaston should be taken with caution in patients suffering from depression, asthma and vaginal bleeding.
Sources:
- "Dufaston" during pregnancy
The dosage of "Duphaston" can only be prescribed by a doctor, based on the condition of the pregnant woman. With the threat of a miscarriage, you can take a double dose of the drug at a time, and then reduce it.
Instruction
"Duphaston" - synthetic, performing the function of natural progesterone. The drug helps to prepare the endometrium of the uterus for pregnancy, and after its onset, save the fetal egg. If the doctor has prescribed this drug for you, then your body lacks its own hormone progesterone and it urgently needs to be replenished so that the pregnancy does not end in a miscarriage or fetus.
Very often, this drug is prescribed even at the stage of pregnancy planning, when it is proved that the level of the hormone progesterone in the woman's body is reduced. But you can get reliable results only after passing the appropriate analysis. If a doctor prescribes a drug for you without a preliminary examination, you should doubt his competence, even if you really want a child and previous pregnancies ended in a miscarriage. The fact is that the cause of past miscarriages could not be a low level of progesterone at all, but a number of other diseases that could lead to such unpleasant ones.
Do not drink Duphaston just in case, because an unauthorized change in hormonal levels can adversely affect your health and in the long run lead to a metabolic failure. How to take Duphaston? If pregnancy occurs after taking the drug for 3-6 menstrual cycles, then you must continue to drink it, otherwise a sharp decrease in the level of this hormone in the blood will lead to a miscarriage. The dosage of the drug is determined by the doctor, but usually it is 20 mcg per day, that is, you need to drink one tablet 2 times a day.
This is a treatment, according to the same scheme, you should take the drug during pregnancy, even if you have not encountered it before. In this case, the indications for are, as a rule, pain in the lower abdomen and spotting. It is necessary to cancel hormone therapy gradually, starting from the 20th week of pregnancy, some women are advised to stop taking Duphaston on the 16th. In any case, you should first consult with your doctor about this.
If you have a sharp question about the threat of a miscarriage, you can take 40 micrograms of the drug at a time, and then reduce the dosage. All this needs to be clarified with the attending physician, who can make a decision after colpocytology, a study that helps assess the condition of the vaginal epithelium.
During treatment with Duphaston, you will experience nausea, headache. This is a normal reaction and should not be feared. The situation is more complicated with allergic reactions and bleeding. These side effects should be reported to your doctor right away. Contraindications to taking the drug are diseases of the heart, liver and sickle cell anemia.
Duphaston is a drug based on dydrogesterone, a component that is an analogue of the natural hormone progesterone. It is prescribed for a lack of this hormone in the female body. Duphaston is prescribed to pregnant women with chronic endometritis, and is also used to prevent the threat of miscarriage or with habitual miscarriage, the causes of which are progesterone deficiency.
Instruction
Duphaston effectively compensates for the lack of progesterone, creating normal conditions for the development of the fetus, and also eliminates uterine hypertonicity, relaxing smooth muscles. To prescribe Duphaston during the dosage is 40 mg (4 tablets). It is taken once. Then appoint 10 mg (1 tablet) of the drug every 8 hours. Reception of Duphaston during pregnancy in this case is continued until the symptoms of a threatened miscarriage completely disappear.
The standard daily dose of the drug for habitual miscarriage, when a woman has already experienced spontaneous abortion several times, is 20 mg. It is divided into two doses during the day. As a rule, this dosage is applied until the 20th week of pregnancy, after which it is gradually lowered.
Cancellation of Duphaston during pregnancy must be agreed with the doctor. In no case should you abruptly stop taking the drug, as this can lead to bleeding or provoke a miscarriage. Withdrawal of the drug is carried out after obtaining normal test results, each day reducing the daily dose by half a tablet or a whole tablet. The Duphaston withdrawal scheme is developed by the doctor on an individual basis and in some cases this process can take several weeks.
Duphaston is not prescribed for individual intolerance to dydrogesterone, as well as for women with certain hereditary diseases (Rotor syndrome and Dubin-Johnson syndrome). In addition, the drug is prescribed with caution to women with diabetes mellitus, disorders of the cardiovascular system, kidney disease, as well as in the presence of pruritus during a previous pregnancy.
Many women who have made the decision to become a mother face the problem of conceiving and bearing a child. The reason for this may be chronic diseases of the internal genital organs, as well as adverse environmental factors. Many women are interested in the question of why Duphaston is prescribed during pregnancy in the early stages. In modern medicine, there are well-established methods for using the drug Duphaston, which contributes to the onset and maintenance of pregnancy.
If a woman decides to use the drug, then she needs to agree on the dosage regimen and dosage with her doctor. The clinical effect of Duphaston on pregnancy has been experimentally proven.
The drug is available in tablet form. The composition of the drug includes components similar in their action to the hormone progesterone. This drug is well tolerated by the female body, without causing side effects. The basis of the action of the drug is the normalization of the activity of the mucous membrane of the uterine cavity (endometrium).
The onset of pregnancy after Duphaston occurs as soon as possible. Unlike its counterparts, this drug does not have a depressant effect on the nervous system, without causing drowsiness and apathy.
Spontaneous abortions most often occur due to increased tone of the smooth muscles of the uterus. The drug Duphaston during pregnancy is prescribed to women in order to relax the uterine muscles. Most often, the drug is recommended in early pregnancy.
Preservation of pregnancy when taking Duphaston is observed in 85% of cases. If a woman has a tendency to increased uterine tone, gynecologists prescribe this remedy even before the baby is conceived.
The main indication for prescribing the drug is insufficient production of the hormone progesterone in the female body. Before starting a substance, a woman must receive laboratory confirmation of a progesterone deficiency.
In the early stages
The main indications for the use of Duphaston in early pregnancy include:
- high risk of spontaneous abortion;
- endometriosis;
- dishormonal bleeding;
- habitual miscarriage.
At a later date
The standard instruction for the use of Duphaston during late pregnancy recommends taking the substance with an increase in the tone of the uterine muscles, resulting in a risk. In this case, we are talking about birth.
The drug is highly effective in relation to infertility caused by hormonal disorders in the body of a woman.
In the vast majority of cases, the drug is favorably tolerated by the woman's body, and pregnancy against the background of Duphaston proceeds favorably. The main contraindication for taking the drug in the early and late stages is the presence of individual hypersensitivity to the components of the drug. Care must be taken in inflammatory diseases of the liver (hepatosis).
Caution is recommended for those women who have previously had cases of an allergic reaction. It is strictly forbidden to combine the drug with alcohol, since the effect of ethyl alcohol on the liver prevents the neutralization of the decay products of Duphaston.
Often, women may experience discharge when taking Duphaston during pregnancy, which are natural in nature.
Instructions for use
In order to get the expected result, it is important to know how to drink Duphaston during pregnancy at different times. The official instructions for the use of the drug involves the use of the drug inside. With the growth of the mucous layer of the uterus (endometriosis), the optimal dosage of the drug is 1 tablet 3 times a day from 5 to 25 days of the menstrual cycle.
If a woman has a risk of spontaneous abortion, the dosage of Duphaston during pregnancy is 4 tablets at a time, after which it is recommended to continue taking the medication 1 tablet every 8 hours, until the alarming symptoms disappear.
Taking Duphaston in the first trimester of pregnancy is most justified. Taking Duphaston with brown discharge during pregnancy will help to avoid bleeding at different times. Colored discharge after Duphaston during pregnancy is a variant of the norm.
With a high risk of premature fetal rejection, a woman is recommended to get advice on how to take Duphaston during pregnancy with such a pathology. The optimal dose of Duphaston during pregnancy is 1 tablet 2 times a day, up to the 20th week of pregnancy.
If a woman is diagnosed with hormonal infertility, the amount of the substance taken is 1 tablet 1 time per day from the 14th to the 25th day of the cycle. The duration of treatment with Duphaston for infertility is at least six months.
For pregnancy, Duphaston and Proginova can be used in combination.
With painful menstruation, it is recommended to use 1 tablet of the substance 2 times a day from the 11th to the 25th day of the cycle. In case of menstrual irregularities and hormonal instability, it is necessary to take 1 tablet 2 times a day from the 5th to the 25th day of the menstrual cycle.
If a woman suffers from amenorrhea, then the essence of drug therapy is the combined use of Duphaston and medications containing estrogens. With amenorrhea, the dosage of the substance is 1 tablet 2 times a day from the 11th to the 25th day of the cycle.
To stop uterine bleeding, a dosage of 1 tablet 2 times a day for 7 days is used.
The attending physician will tell you how much to drink Duphaston during pregnancy.
Distribution and excretion from the body
The absorption of Duphaston tablets during pregnancy into the blood occurs in the intestinal cavity. The maximum content of the active ingredient in the blood plasma is fixed after 1.5-2 hours from the moment of taking the medication. Dufaston is distributed throughout the woman's body through contact with albumin. The chemical transformation of the components of the drug is carried out in the liver tissue, under the action of special enzymes.
The drug is excreted from the body through the urinary system. The duration of the half-life is from 17 to 19 hours. The period of complete elimination takes up to 70 hours. In the absence of renal pathology, there were no problems with the excretion of the substance from the woman's body.
How long is the drug used?
In the first trimester of pregnancy, the body of the expectant mother experiences the greatest need for progesterone. In most cases, the use of Duphaston during pregnancy is justified until the 20th week, since its further use loses all meaning. The use of funds in the early stages has its own principles:
- it is strictly forbidden to independently replace the drug with its analogues;
- taking the drug is carried out according to the medical scheme;
- If you experience anxiety symptoms, it is recommended to contact your doctor immediately.
You can check with your doctor for how long to take Duphaston during pregnancy.
How to cancel Duphaston?
Proper drug withdrawal is a sensitive issue that must be approached gradually. The standard tactic is to gradually reduce the dosage by 1/2 tablet of the drug every 7 days. This will avoid sudden changes in hormonal levels and pregnancy failure.
If a pregnant woman takes 2 tablets per day, then she needs to reduce the daily dosage to 1.5 tablets. After another week, the dosage is 1 tablet per day. Thus, the dose of the drug is reduced to zero.
The attending physician will tell you how much to take Duphaston during pregnancy and how to cancel it correctly. It may take several weeks to completely stop the drug.
Side effects
The drug Duphaston during pregnancy causes side effects in rare cases:
- Adverse reactions from the immune system are manifested in the form of allergic reactions of varying severity.
- With the formation of adverse reactions from the digestive organs, the functional state of the liver is disturbed, which affects the levels of bilirubin in the blood.
- The function of hematopoiesis is inhibited, as a result of which hemoglobin falls.
- A negative reaction can be obtained from the organs of the reproductive system. The therapeutic dosage of the drug causes bleeding in some women, which is treatable with dose adjustment of the drug.
Speaking about how Duphaston affects pregnancy, we can conclude that the effect of this drug is multifaceted.
Since the start of the release of the drug in the practice of medical specialists, there have been no cases of negative reactions provoked by an overdose of the drug. That is why the question of whether Duphaston is harmful during pregnancy disappears by itself.
It is not recommended to combine taking Duphaston at the beginning of pregnancy and throughout it with drugs such as Phenobarbital and Rifampicin. Such experiments can lead to inhibition of the medicinal effect of the drug.
Taking the drug Duphaston to maintain pregnancy must first be agreed with the attending gynecologist. Before starting therapy with progesterone preparations, it is recommended to familiarize yourself with the possible consequences. The process of hormone replacement therapy should take place under strict quality control of treatment.
The ingestion of the substance into the body does not cause disturbances in the organs of the urinary system. The active components of the drug do not affect the ability to perform precise work and drive a vehicle. The characteristic signs of pregnancy on Duphaston do not differ from the standard symptoms.
Before starting the use of the drug, it is necessary to pay attention to the selection of a therapeutic dosage. This issue is dealt with by a medical specialist.
Useful video with expert advice on taking progesterone during pregnancy
Dufaston has proven itself in solving many problems of women's health. It is successfully used when planning conception and when it occurs. Duphaston during pregnancy is necessary for many properties. The opinions and experience of gynecologists regarding the drug are almost always positive.
Dufaston has become the most commonly used drug during pregnancy due to its ability to preserve it, especially in the early stages.
The action is based on the replenishment of progesterone - the main hormone of pregnancy. It is responsible for the elasticity of the walls of the uterus, keeping the cervix closed, and affects the proper development of the fetus.
Duphaston during pregnancy: indications
The drug is prescribed for:
- threat of interruption;
- miscarriages, non-developing pregnancies;
- insufficiency of progesterone;
- age pregnancy;
- prevention of these conditions.
Harm as such from its use was not noticed, and the benefits are obvious and justified by the result. Practice shows a good percentage of avoiding miscarriages when taking Duphaston during pregnancy.
Instructions for use
The prescribed dosage of the drug depends on the degree and severity of the threat of abortion:
- For therapeutic purposes, Duphaston is prescribed 1 ton per day up to 26 weeks.
- With the threat of miscarriage, bleeding or non-standard discharge, a single dose of 4 tablets is prescribed, then 1 tablet 6 hours later until the symptoms stop.
- With a decrease in the risk of abortion in the first trimester and stabilization of the condition, the dosage of the drug is gradually reduced. Then they lead to a standard reception of 1 t. 2 r. per day after 12 hours.
How long to drink
Until what week and how many tablets per day to drink - the gynecologist who observes the pregnant woman decides. Most often, Duphaston is taken up to 16 weeks, then gradually reducing the dose, the drug is canceled.
With a more difficult course of pregnancy, the use is extended to 26 weeks, adjusting the daily dose. After 26 weeks, with the continued threat of abortion or the risk of premature birth, it is advisable to replace duphaston with Utrozhestan and its vaginal use.
Contraindications
Contraindications to the use of Duphaston:
- breast-feeding;
- severe liver damage;
- individual intolerance to the drug.
Possible side effects
Possible side effects:
- emotional instability;
- headache;
- feeling tired;
- weakness;
- insomnia;
- lack of appetite.
All these signs accompany the normal course of pregnancy, their appearance is not always associated with taking the drug.
There are many myths and horror stories about the use of hormonal drugs, and Duphaston, in particular:
- uncontrolled weight gain will occur;
- very strong growth of hair on the body is possible;
- many side effects.
All these conjectures are unfounded, not confirmed by practice and experience. The composition of the drug and the amount of the active substance are selected in accordance with the latest scientific data as harmlessly as possible for the body of a pregnant woman.
What effect?
In its composition, Duphaston is a synthetic progesterone, that is, it is a hormone, so you need to take the medicine strictly at the same time.
Even in difficult cases, the timely start of taking Duphaston during early pregnancy, in combination with other measures, prevents the threat of miscarriage.
Taking the drug makes it possible for the fetus to develop correctly during the laying of all internal organs and systems.
With tone, Duphaston helps relieve the increased tension of the walls of the uterus, return pregnancy to normal.
Cancellation scheme
When taking Duphaston, you should not abruptly stop drinking it, because this can cause bleeding. To stop the drug, you need to gradually reduce its dosage in order to carefully reduce its use to nothing.
A possible scheme for reducing the amount and canceling Duphaston:
- When switching from 2 tablets per day, you can reduce the dose in one of the doses by 0.5 tablets.
- After 2 days, reduce the dose of another dose by 0.5 tablets.
- After the next 2 days, reduce the dose of one of the doses by another 50% and so on to 0.
The action of the drug is based on the hormonal support of the reproductive system. We use it to normalize the menstrual cycle in the usual "non-pregnant" position. In this case, it is precisely this property of Duphaston that is used to give bleeding to cancel the drug, which is unacceptable during pregnancy.
On the video about the appointment of Duphaston to pregnant women
What should I do if I forgot to take a pill?
What to do if you accidentally miss a pill? It should be taken as soon as possible, as quickly as possible, and the entire reception schedule is then shifted by this number of hours.
Price
The cost of Duphaston is approximately 600 rubles. for a pack. The product is available in tablets, packs of 20 pieces.
The use of Duphaston is safe for the unborn child and the health of the mother. Reception is not tied to food intake, the drug does not affect the ability to drive, does not require special storage conditions.
Are there analogues?
Analogues - Utrozhestan, Prajisan. The price of Prajisan is somewhat lower.
There are some features of receiving analogues. Duphaston is taken orally, and Utrozhestan and Prajisan can be used as vaginal suppositories.
In the later stages, this is justified by the fact that the local application of progesterone has a positive effect on the cervix, gives less stress on the liver and digestive tract. The recommendations of the doctor leading the pregnancy are of decisive importance here.
Any woman who dreams of being a mother, but due to some physiological characteristics, cannot become one, is in a stressful state. This further depresses her reproductive system and delays the long-awaited pregnancy. That is why researchers around the world are deeply studying the issue of infertility and are developing new drugs to solve this problem.
Such a drug is Duphaston. With the help of this medicine, doctors help women who zealously fight for the right to be a mother to become pregnant and bear a baby.
Information about Duphaston: composition and its positive properties
The main active ingredient of Duphastoan is dydrogesterone. One dosage tablet contains 10 or 20 mg of Dydrogesteronum. This is a synthetic analogue of the female hormone of the reproductive system - progesterone, which ensures the safe engraftment of the egg and "protects" it.
A few years ago, synthetic hormones were produced in ampoules and used intravenously. Such treatment during pregnancy frightened many women. Now the drug, tableted and in a convenient blister; it is easy to take inside while at home. In addition, dydrogesterone acts directly on the uterus.
Indications for the use of Duphaston
The reason for the appointment of Duphaston are any disorders caused by luteal insufficiency. Normally, progesterone is produced by the corpus luteum up to 16 weeks. The placenta then produces hormones. If such a process is violated, Duphaston is prescribed. It delicately enters the bloodstream and performs its functions.
But not every daub in the early stages of pregnancy needs to take Duphaston. There are many other factors that can lead to miscarriage or pregnancy failure. That is why it is necessary to approach the issue comprehensively: take tests for hormone levels, smears for hidden infections, and exclude other pathologies.
Important! Taking Duphaston after 20 weeks is not advisable for prophylaxis.
Disorders that are regulated by hormone replacement therapy with Duphaston include:
- Threatened abortion (uterine bleeding from the genitals, acute pain in the abdomen).
- Endometriosis (if it existed before pregnancy).
- Pregnancy due to hormonal imbalance.
- Detachment of the placenta.
Contraindications and side effects of Duphaston
The main contraindications for taking Duphaston during early pregnancy:
- Individual hypersensitivity to dydrogesterone or other components of the drug.
- Severe liver damage is not inflammatory.
- The presence of progestogen-dependent oncological tumors.
All medications cause a number of undesirable reactions of the body. Fortunately, such unpleasant "surprises" happen quite rarely. What are the side effects of taking Duphaston with the threat of miscarriage in the early stages? And what do women most often complain about?
Duphaston during early pregnancy causes the following side effects:
- Strong headache.
- Changes in the breast, as a result of an excess of hormones in the blood.
- Exacerbation of chronic liver diseases.
- Various allergic reactions.
If at least one of the symptoms has visited a woman in position, she should consult a doctor to review the dosage or replace Duphaston with another drug.
The main question that worries expectant mothers: does Duphaston affect the development of the child? Many studies that have been conducted over several years have proven the absence of a negative factor for both the mother and her baby. Synthetic hormone does not cause fetal malformations. In a child born from a mother who took Duphaston, metabolic processes are not disturbed and there are no neurological pathologies. It belongs to a new generation of hormones that do not affect weight, changes in the timbre of the voice and hair growth.
Features of the use of Duphaston: dosage, duration of administration and withdrawal of the drug
The first trimester is the most dangerous and responsible period. If something threatens pregnancy, then first of all, the correct course of treatment and the fulfillment of all the doctor's prescriptions are needed, which will tell you how to take Duphaston in the early stages of pregnancy. Each woman is selected an individual scheme for taking pills.
Important! You can not independently change the treatment regimen, reduce or increase the number of pills you drink, skip a dose and cancel Duphaston on your own. This behavior can lead to miscarriage and heavy bleeding!
Threatened abortion. Immediately appoint 40 mg of dydrogesterone at a time, and then every eight hours, 10 mg. After the threat disappears, they take an effective dose for 7 days and then begin to reduce it.
habitual abortion. Dufaston is started before pregnancy at a dosage of 10 mg in the second phase of the menstrual cycle. After conception, the drug is not canceled. Duphaston is taken during early pregnancy, in a dosage taking into account the condition up to the 20th week of pregnancy.
Particular care should be taken to cancel the drug. As a rule, the dose is reduced by 5-10 mg every week, in some cases they take 1 tablet every other day, then half a tablet, etc.
Important! How exactly you reduce the dosage can only be decided by a doctor!
Conclusion
What you need to remember about the expectant mother who takes Duphaston:
- Dufaston temporarily takes over the duties of some of the functions of your reproductive system, thereby maintaining the pregnancy.
- How to drink Duphaston in the early stages of pregnancy is decided only by a gynecologist.
- Duphaston has very few contraindications, and side effects occur in isolated cases.
- Self-cancellation of the drug is unacceptable.
- In the presence of hormonal disorders, Duphaston is prescribed at the planning stage.
- It does not harm your unborn baby.